Vasoactive intestinal peptide
VIP
Cited range Neuropeptide
What it is
VIP is an endogenous neuropeptide in the secretin/glucagon family. It is a serious signaling molecule in gut, lung, and circadian biology — not a mild “repair additive.”
Benefits in plain language
What researchers and reference users usually mean when they talk about this compound. These are study themes and common claims — not a promise that it will do this in you.
- Vasoactive intestinal peptide relaxes smooth muscle and modulates immunity and circadian lung chemistry.
- Research and some compounded nasal use show up in mold / inflammatory / circadian conversations.
- Blood pressure drop and flushing are on-brand for a vasoactive peptide.
If a branded, FDA-approved product exists, that label is the only dose that is actually authorized. Research-chemical vials are a different object.
Mechanism of action
VPAC1/VPAC2 receptors raise cAMP and relax smooth muscle, with immune-modulating effects in several tissues.
Possible side effects / caveats
Blood-pressure drop, flushing, and GI motility changes are physiologically plausible. Inhaled vs injected are different drugs in practice.
Protocol ranges
| Source tier | Amount | Frequency / duration | Notes |
|---|---|---|---|
| Literature | Highly protocol-specific | Do not generalize | Look up the exact trial before citing a number |