Selank

Cited range Intranasal literature

ClassSynthetic tuftsin analog

Regulatory noteUsed in Russia; not US-approved

Common routeIntranasal

Often paired withSemax in nootropic writeups

What it is

Selank is a heptapeptide analog of tuftsin developed for anxiety and asthenia research. Like Semax, most clinical use is outside the US.

Benefits in plain language

What researchers and reference users usually mean when they talk about this compound. These are study themes and common claims — not a promise that it will do this in you.

A tuftsin-based Russian peptide for anxiety and focus, usually nasal.
People describe it as “calm but not dumb” — less jitter than some stimulants, less fog than some sedatives.
Evidence base is mostly Russian clinical tradition plus mechanism papers.

If a branded, FDA-approved product exists, that label is the only dose that is actually authorized. Research-chemical vials are a different object.

Mechanism of action

Proposed GABAergic and enkephalin-system modulation plus immune-adjacent tuftsin biology. It is framed as anxiolytic rather than stimulant.

Possible side effects / caveats

Nasal irritation, fatigue or paradoxically activated mood in some reports. Evidence quality is mixed by Western trial standards.

Protocol ranges

Source tier	Amount	Frequency / duration	Notes
Cited range	250–500 mcg	1–2× daily intranasal	Common secondary window
Cited range	300–900 mcg/day	Split nasal sprays	Upper talk in nootropic references