NAD+ + MOTS-c + 5-Amino-1MQ · also MitoPrime
Mito Prime
Blend
What it is
Mito Prime (MitoPrime) is a shop blend, usually NAD+ 100 mg + MOTS-c 10 mg + 5-Amino-1MQ 10 mg (120 mg). Only MOTS-c is a true peptide. NAD+ is a coenzyme. 5-Amino-1MQ is a small-molecule NNMT blocker already in this library as its own page.
Benefits in plain language
What researchers and reference users usually mean when they talk about this compound. These are study themes and common claims — not a promise that it will do this in you.
- What people want: cellular energy (NAD+), exercise-mimetic metabolic signaling (MOTS-c), and a fat-cell NAD-sparing angle (5-Amino-1MQ) in one vial.
- The mix is 10:1:1 by milligrams — almost all NAD+ by weight.
- 5-Amino-1MQ is already documented solo here. This page is only the branded combo.
If a branded, FDA-approved product exists, that label is the only dose that is actually authorized. Research-chemical vials are a different object.
Mechanism of action
NAD+: redox cofactor for sirtuins and PARPs. MOTS-c: mitochondrial-encoded peptide, AMPK-linked metabolic models. 5-Amino-1MQ: NNMT inhibition that can spare NAD+ in fat-cell research. Three different chemistries, one cake.
Possible side effects / caveats
NAD+ flush or tightness, unknown 5-Amino-1MQ human dose window, MOTS-c still early in people. Fixed ratio again.
Protocol ranges
| Source tier | Amount | Frequency / duration | Notes |
|---|---|---|---|
| Common vendor vial | 100 mg NAD+ + 10 mg MOTS-c + 10 mg 5-Amino-1MQ | 120 mg total | Confirm COA |
| Cited chatter | Daily mixed draw in secondary blogs | Often multi-week | Not a label |
| See also | NAD+, MOTS-c, 5-Amino-1MQ | Solo pages |