Macimorelin

Label Diagnostic

ClassGhrelin-receptor agonist

Typical routes in papersOral diagnostic

Half-life contextHours

EvidenceFDA-approved diagnostic

What it is

Macimorelin (Macrilen) is an oral ghrelin agonist used as a one-time test: does the pituitary still release GH?

Benefits in plain language

What researchers and reference users usually mean when they talk about this compound. These are study themes and common claims — not a promise that it will do this in you.

Benefit is diagnostic — replace an insulin-tolerance GH test with a drink in selected adults.
It is not a nightly secretagogue protocol.
Included so “oral GHRP” searches hit the real approved use.

If a branded, FDA-approved product exists, that label is the only dose that is actually authorized. Research-chemical vials are a different object.

Mechanism of action

GHSR agonism provokes a measurable GH peak for lab sampling.

Possible side effects / caveats

Dysgeusia, headache, fatigue; mis-use as a daily oral GH drug is off-script.

Protocol ranges

Source tier	Amount	Frequency / duration	Notes
Label	0.5 mg/kg oral	Single diagnostic dose after fast	Adult GH deficiency testing

Numbers below and above are literature or community pointers, not a treatment plan. Approved products, when they exist, follow the official label — not a research vial.