Library / Redox / mito / Humanin-G (HNG)
S14G-Humanin
Humanin-G (HNG)
Cited range
ClassMitochondrial-derived peptide analog
Typical routes in papersResearch SC / experimental
Half-life contextShort
EvidencePreclinical; stronger in models than native humanin
What it is
HNG is humanin with a glycine swap that makes the cell-survival signal stronger in experiments.
Benefits in plain language
What researchers and reference users usually mean when they talk about this compound. These are study themes and common claims — not a promise that it will do this in you.
- Research hopes: protect neurons and other cells under metabolic or toxic stress.
- Same family as MOTS-c and humanin — mitochondrial postcards, not GH.
- Human protocols are guessed, not labeled.
If a branded, FDA-approved product exists, that label is the only dose that is actually authorized. Research-chemical vials are a different object.
Mechanism of action
Mitochondrial-derived peptide analog engaging proposed CNTFR/gp130 and intracellular survival pathways; S14G increases potency in models.
Possible side effects / caveats
Unknown human safety at “wellness” doses.
Protocol ranges
| Source tier | Amount | Frequency / duration | Notes |
|---|---|---|---|
| Anecdote / early translation | Sub-mg to low-mg weekly class in scattered notes | Unstandardized | Treat as unsettled |
Numbers below and above are literature or community pointers, not a treatment plan. Approved products, when they exist, follow the official label — not a research vial.