Hexapeptide ghrelin mimetic
GHRP-6
Cited range Strong appetite signal
What it is
GHRP-6 is a six-amino-acid ghrelin mimetic from the early secretagogue series. It is less selective than later analogs.
Benefits in plain language
What researchers and reference users usually mean when they talk about this compound. These are study themes and common claims — not a promise that it will do this in you.
- Similar GH pulse to GHRP-2 with an even louder hunger signal.
- Useful in write-ups when the goal was eat-more plus GH. Annoying if the goal was cut.
- Same family caveats: water, tingling, appetite, and pituitary over-asking if abused.
If a branded, FDA-approved product exists, that label is the only dose that is actually authorized. Research-chemical vials are a different object.
Mechanism of action
GHSR-1a agonism with notable gastric and appetite effects. GH release occurs alongside more off-axis hormone noise than ipamorelin in the usual comparison tables.
Possible side effects / caveats
Marked hunger, cortisol/prolactin changes, water retention, tiredness in some reports, and local reactions.
Protocol ranges
| Source tier | Amount | Frequency / duration | Notes |
|---|---|---|---|
| Cited range | 100–300 mcg per pulse | 1–3× daily | Common catalog talk |