Pralmorelin · ghrelin-receptor agonist
GHRP-2
Cited range
What it is
GHRP-2 (pralmorelin) is an older growth-hormone-releasing peptide used in some countries as a diagnostic GH stimulant. Research catalogs still list it as a secretagogue.
Benefits in plain language
What researchers and reference users usually mean when they talk about this compound. These are study themes and common claims — not a promise that it will do this in you.
- An older ghrelin-mimic that strongly pulses GH — and often hunger.
- People used it for GH output, sleep, and appetite when that was wanted (hardgainers).
- More cortisol/prolactin chatter than ipamorelin in the comparison tables people share.
- Mostly superseded in community stacks by ipamorelin, but still in the archive.
If a branded, FDA-approved product exists, that label is the only dose that is actually authorized. Research-chemical vials are a different object.
Mechanism of action
Ghrelin-receptor (GHSR-1a) agonism releases GH and commonly increases appetite more than ipamorelin. Cortisol and prolactin spillover is described as higher than ipamorelin in comparative writeups.
Possible side effects / caveats
Hunger, water retention, tingling, cortisol/prolactin drift, and injection-site reactions.
Protocol ranges
| Source tier | Amount | Frequency / duration | Notes |
|---|---|---|---|
| Cited range | 100–300 mcg per pulse | 1–3× daily | Typical secondary window |