GHRH analog + GHRP · most common GH-axis blend
CJC-1295 + Ipamorelin
Blend
What it is
The default “GH peptide blend” is CJC-1295 (almost always the no-DAC / Mod GRF 1-29 version) plus ipamorelin in one vial, often 5 mg + 5 mg or 10 mg total. Two doors into a GH pulse: GHRH receptor and ghrelin receptor.
Benefits in plain language
What researchers and reference users usually mean when they talk about this compound. These are study themes and common claims — not a promise that it will do this in you.
- What people want: a bigger, cleaner GH pulse than either peptide alone, with less hunger than old GHRP-6.
- Confirm DAC vs no-DAC on the label. DAC CJC changes the schedule from nightly pulses to a flatter weekly-ish level.
- See the solo CJC-no-DAC and Ipamorelin pages for mechanisms.
If a branded, FDA-approved product exists, that label is the only dose that is actually authorized. Research-chemical vials are a different object.
Mechanism of action
Mod GRF / CJC-no-DAC amplifies a GHRH-style pulse. Ipamorelin triggers GHSR. Together they are the textbook secretagogue pair in community protocols.
Possible side effects / caveats
Water, tingling, tired-hungry if the GHRP share is high, and pituitary overuse talk if someone runs it without breaks. DAC version is a different kinetic.
Protocol ranges
| Source tier | Amount | Frequency / duration | Notes |
|---|---|---|---|
| Common vial | 5 mg CJC-no-DAC + 5 mg ipamorelin | Nightly mixed draw in citations | Confirm no-DAC |
| Cited pulse | 100–300 mcg of the mix per injection | 1–3× daily or bedtime | Community |
| See also | CJC-1295 no DAC, Ipamorelin, CJC-1295 DAC | Parts |