Library / GH axis / Anamorelin
Oral GHSR agonist · cachexia
Anamorelin
Trial / regional
ClassGhrelin-receptor agonist
Typical routes in papersOral in development / some regions
Half-life contextHours
EvidenceCachexia trials; regional approvals vary
What it is
Anamorelin is an oral ghrelin-mimic built for cancer cachexia — the “wasting despite eating” problem.
Benefits in plain language
What researchers and reference users usually mean when they talk about this compound. These are study themes and common claims — not a promise that it will do this in you.
- Trial aims: appetite up, lean mass up, in sick patients who are melting away.
- It is the clinical cousin of the injectable GHRPs, in a pill.
- Not approved everywhere; not a beach-cut agent.
If a branded, FDA-approved product exists, that label is the only dose that is actually authorized. Research-chemical vials are a different object.
Mechanism of action
GHSR (GHS-R1a) agonism increases GH secretion and hunger signaling.
Possible side effects / caveats
Hyperglycemia, edema, fatigue, and the ethics of using a cachexia drug as a lifestyle secretagogue.
Protocol ranges
| Source tier | Amount | Frequency / duration | Notes |
|---|---|---|---|
| Trial / regional labels | 50–100 mg oral class in publications | Daily | Jurisdiction-specific |
Numbers below and above are literature or community pointers, not a treatment plan. Approved products, when they exist, follow the official label — not a research vial.